Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426433 | 0.80 | HTR2B (0.36) | KMT2AHSD11B1ALDH1A1CYP3A4TSHR | |
| SCHEMBL3410793 | 0.77 | PLA2G7 (0.37) | PLA2G7KMT2APOLBHSD11B1CYP2A6 | |
| SCHEMBL6852286 | 0.75 | KMT2A (0.43) | PLA2G7KMT2APOLBHSD11B1CYP2A6 | |
| SCHEMBL5086316 | 0.74 | ALKBH3 (0.35) | KMT2APOLBALDH1A1CYP2C19LMNA | |
| SCHEMBL13176930 | 0.74 | PLA2G7 (0.50) | PLA2G7KMT2APOLBHSD11B1CYP2A6 | |
| SCHEMBL5993764 | 0.73 | PTGDR2 (0.41) | KMT2AALDH1A1CYP2C19NPC1RAB9A | |
| SCHEMBL277914 | 0.71 | PLA2G7 (0.67) | PLA2G7KMT2APOLBHSD11B1CYP2A6 | |
| SCHEMBL3410828 | 0.71 | ALDH1A1 (0.37) | KMT2APOLBCYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL5318809 | 0.71 | — | — | |
| SCHEMBL1980000 | 0.70 | PLA2G7 (0.51) | PLA2G7KMT2APOLBHSD11B1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072207-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |