Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.54 |
| ▸ | BHMT | Q93088 | 4/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19800782 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2BHMTPAMBHMT2 | |
| SCHEMBL11865270 | 0.85 | GRIK1 (0.56) | GRIK1GRIK2PAMKIF11GRIK3 | |
| SCHEMBL11865263 | 0.85 | GRIK1 (0.56) | GRIK1GRIK2PAMKIF11GRIK3 | |
| SCHEMBL11865255 | 0.85 | GRIK1 (0.56) | GRIK1GRIK2PAMKIF11GRIK3 | |
| SCHEMBL19800485 | 0.81 | BHMT (0.58) | GRIK1GRIK2BHMTBHMT2GRIK3 | |
| SCHEMBL19800483 | 0.81 | BHMT (0.58) | GRIK1GRIK2BHMTBHMT2GRIK3 | |
| SCHEMBL10990326 | 0.80 | PAM (0.55) | GRIK1GRIK2PAM | |
| SCHEMBL1865554 | 0.76 | GRIK1 (0.73) | GRIK1GRIK2PAMGRIK3 | |
| SCHEMBL1865552 | 0.76 | GRIK1 (0.73) | GRIK1GRIK2PAMGRIK3 | |
| SCHEMBL504608 | 0.76 | GRIK1 (0.73) | GRIK1GRIK2PAMGRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9879043-B1 | Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2018-01-30 | — | — | US | disclosed |