Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 12/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 11/20 | 0.56 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865263 | 1.00 | GRIK1 (0.56) | GRIK1GRIK2PAMKIF11HTR2A | |
| SCHEMBL11865255 | 1.00 | GRIK1 (0.56) | GRIK1GRIK2PAMKIF11HTR2A | |
| SCHEMBL4223925 | 0.88 | KIF11 (0.46) | GRIK1GRIK2KIF11GRIK3 | |
| SCHEMBL4223920 | 0.88 | KIF11 (0.46) | GRIK1GRIK2KIF11GRIK3 | |
| SCHEMBL19800778 | 0.85 | GRIK1 (0.54) | GRIK1GRIK2PAMKIF11GRIK3 | |
| SCHEMBL19800782 | 0.85 | GRIK1 (0.54) | GRIK1GRIK2PAMKIF11GRIK3 | |
| SCHEMBL11568907 | 0.79 | ARG2 (0.52) | GRIK1GRIK2KIF11GRIK3 | |
| SCHEMBL1865552 | 0.78 | GRIK1 (0.73) | GRIK1GRIK2PAMHTR2AGRIK3 | |
| SCHEMBL504608 | 0.78 | GRIK1 (0.73) | GRIK1GRIK2PAMHTR2AGRIK3 | |
| SCHEMBL1865554 | 0.78 | GRIK1 (0.73) | GRIK1GRIK2PAMHTR2AGRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950387-A | LIPID DISORDERS, ATHEROMATIC CONDITIONS | RECHERCHES PHARMACEUTIQUES ET SCIENTIFIQUES (FR) | 1976-04-13 | — | — | US | disclosed |