Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.63 |
| ▸ | TUBB | P07437 | 2/20 | 0.63 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.63 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.63 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.63 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.63 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.63 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.63 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.63 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.63 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.63 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.63 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.63 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19801012 | 0.93 | TUBB4A (0.68) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19801014 | 0.91 | TUBB4A (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19800962 | 0.91 | TUBB1 (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20537607 | 0.91 | BACE1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20537609 | 0.91 | BACE1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20538635 | 0.91 | ALDH1A1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20538633 | 0.91 | ALDH1A1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19801048 | 0.90 | BCHE (0.58) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19801011 | 0.90 | TUBB4A (0.64) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19801010 | 0.90 | TUBB4A (0.64) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183230-B1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-10-24 | — | — | EP | claimed |
| US-9878977-B2 | N-((3,4,5-trimethoxystyryl)aryl)cinnamamide compounds as potential anticancer agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-01-30 | — | — | US | claimed |