Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 5/20 | 0.51 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19281484 | 0.84 | DDR1 (0.48) | DDR1DDR2ABL1BCROPRM1 | |
| SCHEMBL19284497 | 0.82 | ALDH1A1 (0.49) | OPRM1OPRD1OPRK1OGFRL1HDAC11 | |
| SCHEMBL16775545 | 0.80 | OPRM1 (0.42) | DDR1DDR2ABL1BCROPRM1 | |
| SCHEMBL27082281 | 0.79 | MEN1 (0.47) | NPC1RAB9AKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL15000524 | 0.79 | OPRM1 (0.41) | DDR1DDR2ABL1BCROPRM1 | |
| SCHEMBL17869278 | 0.79 | NPC1 (0.58) | OPRM1OPRD1OPRK1OGFRL1HDAC6 | |
| SCHEMBL19281454 | 0.78 | DDR1 (0.61) | DDR1DDR2ABL1BCR | |
| SCHEMBL309165 | 0.77 | MAOA (0.50) | KDM4EALDH1A1ACACBLIPESRD5A1 | |
| SCHEMBL13181779 | 0.75 | ACACB (0.47) | OPRM1OPRD1OPRK1OGFRL1HDAC6 | |
| SCHEMBL27949705 | 0.75 | ACACB (0.45) | OPRM1OPRD1OPRK1OGFRL1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370360-B2 | Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180022730-A1 | SMALL-MOLECULE INHIBITORS TARGETING DISCOIDIN DOMAIN RECEPTOR 1 AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370360-B2 | Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof | DDR1, DDR2, DDRGK1 | DDR1 1/4885DDR2 2/4885ABL1 2480/4885 |
| US-20180022730-A1 | SMALL-MOLECULE INHIBITORS TARGETING DISCOIDIN DOMAIN RECEPTOR 1 AND USES THEREOF | DDR1, DDR2, DDRGK1 | DDR1 1/4885DDR2 2/4885ABL1 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.