Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13619364 | 0.80 | HPGDS (0.43) | HPGDSTRPV1 | |
| SCHEMBL26828845 | 0.77 | HPGDS (0.33) | HPGDSTRPV1 | |
| SCHEMBL10249921 | 0.72 | KIF11 (0.38) | TRPV1 | |
| SCHEMBL25878168 | 0.67 | CLK1 (0.45) | — | |
| SCHEMBL29297291 | 0.66 | HSP90AA1 (0.32) | — | |
| SCHEMBL22446609 | 0.66 | TRPV1 (0.36) | TRPV1 | |
| SCHEMBL19386405 | 0.66 | HPGDS (0.40) | HPGDS | |
| SCHEMBL20932781 | 0.65 | PDGFRB (0.41) | TRPV1 | |
| SCHEMBL14327674 | 0.63 | CCR1 (0.52) | — | |
| SCHEMBL21497381 | 0.62 | PRKCZ (0.35) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022730-A1 | SMALL-MOLECULE INHIBITORS TARGETING DISCOIDIN DOMAIN RECEPTOR 1 AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022730-A1 | SMALL-MOLECULE INHIBITORS TARGETING DISCOIDIN DOMAIN RECEPTOR 1 AND USES THEREOF | DDR1, DDR2, DDRGK1 | HPGDS 1535/4885TRPV1 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.