Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236343 | 0.89 | APP (0.53) | APPRPS6KA2MAP4K1KCNN4NFE2L2 | |
| SCHEMBL1133437 | 0.87 | APP (0.55) | APPALDH1A1KDM4ETDP1CA12 | |
| SCHEMBL4230789 | 0.86 | MAP4K1 (0.52) | RPS6KA2MAP4K1ACHENFE2L2ALDH1A1 | |
| SCHEMBL2233191 | 0.83 | APP (0.52) | APPALDH1A1KDM4ETDP1CA12 | |
| SCHEMBL20983131 | 0.83 | RPS6KA2 (0.47) | RPS6KA2MAP4K1ACHENFE2L2ALDH1A1 | |
| SCHEMBL10227251 | 0.83 | APP (0.55) | APPRPS6KA2KCNN4NFE2L2MAPK14 | |
| SCHEMBL17241679 | 0.81 | APP (0.46) | APPRPS6KA2MAP4K1KCNN4NFE2L2 | |
| SCHEMBL17807326 | 0.80 | S1PR1 (0.48) | APPRPS6KA2MAP4K1KCNN4ALDH1A1 | |
| SCHEMBL9680975 | 0.80 | ALDH1A1 (0.55) | APPALDH1A1KDM4ETDP1CA12 | |
| SCHEMBL21277121 | 0.80 | MAPT (0.45) | ALDH1A1KDM4EL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018016742-A1 | NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | 주식회사 엘지화학 | 2018-01-25 | — | — | WO | disclosed |