Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | FGB | P02675 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133437 | 0.88 | APP (0.55) | ALDH1A1TDP1ADRA2BPTGS1MEN1 | |
| SCHEMBL5451198 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TDP1ADRA2BPTGS1MEN1 | |
| SCHEMBL2233191 | 0.85 | APP (0.52) | ALDH1A1TDP1ADRA2BPTGS1MEN1 | |
| SCHEMBL2939502 | 0.82 | MEN1 (0.54) | ALDH1A1TDP1ADRA2BPTGS1MEN1 | |
| SCHEMBL3786465 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TDP1ADRA2BPTGS1MEN1 | |
| SCHEMBL19802148 | 0.80 | APP (0.47) | ALDH1A1TDP1MEN1KMT2ARAB9A | |
| SCHEMBL9678804 | 0.80 | CYP3A4 (0.54) | ALDH1A1TDP1ADORA2ARAB9ASMN1; SMN2 | |
| SCHEMBL3794845 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TDP1ADORA2ASMN1; SMN2KDM4E | |
| SCHEMBL18837747 | 0.80 | HSD11B1 (0.47) | ALDH1A1TDP1DPP4CYP3A4 | |
| SCHEMBL397261 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TDP1ADRA2BPTGS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |