SCHEMBL4236343

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Isothiocyanate SCHEMBL29287692	0.89	APP (0.44)	APPNFE2L2CA12CA1CA2
	SCHEMBL10227251	0.89	APP (0.55)	APPNFE2L2CA12CA1CA2
	SCHEMBL19802148	0.89	APP (0.47)	APPNFE2L2CA12CA1CA2
	SCHEMBL17241679	0.87	APP (0.46)	APPNFE2L2CA12CA1CA2
	SCHEMBL17836851	0.84	RPS6KA2 (0.52)	NFE2L2CA1CA2CA7CA9
	SCHEMBL16109429	0.84	APP (0.50)	APPNFE2L2CA12CA1CA2
	SCHEMBL2092087	0.84	APP (0.50)	APPNFE2L2CA12CA1CA2
	SCHEMBL18338826	0.83	NFE2L2 (0.48)	APPNFE2L2CA12CA1CA2
	SCHEMBL22285911	0.83	CA12 (0.52)	APPNFE2L2CA12CA1CA2
	SCHEMBL27341088	0.82	TOP1 (0.47)	NFE2L2CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.