Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29215224 | 0.92 | ALDH1A1 (0.47) | ALDH1A1PDE4BHSD11B1SMN1; SMN2ELANE | |
| SCHEMBL30234226 | 0.92 | ALDH1A1 (0.47) | ALDH1A1PDE4BHSD11B1SMN1; SMN2ELANE | |
| SCHEMBL13072306 | 0.90 | ALDH1A1 (0.45) | ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB | |
| SCHEMBL25082886 | 0.90 | ALDH1A1 (0.45) | ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB | |
| SCHEMBL340847 | 0.88 | MALT1 (0.38) | ALDH1A1SMN1; SMN2POLBKDM4ENPC1 | |
| SCHEMBL13101581 | 0.88 | KDM4E (0.43) | ALDH1A1SMN1; SMN2POLBKDM4ENPC1 | |
| SCHEMBL30234732 | 0.88 | ALDH1A1 (0.43) | ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB | |
| SCHEMBL29215253 | 0.88 | ALDH1A1 (0.43) | ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB | |
| SCHEMBL951462 | 0.87 | SMN1; SMN2 (0.52) | ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB | |
| SCHEMBL29558577 | 0.87 | ALDH1A1 (0.48) | ALDH1A1PDE4BHSD11B1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586753-B2 | Process for the preparation of 1-alkyl and 1-aryl-5-pyrazolecarboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-19 | — | — | US | disclosed |
| US-8586753-B2 | Process for the preparation of 1-alkyl and 1-aryl-5-pyrazolecarboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-19 | — | — | US | disclosed |
| EP-2513063-B1 | Method for manufacturing 1-alkyl-/1-aryl-5-pyrazolcarbonic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-2513063-B1 | Method for manufacturing 1-alkyl-/1-aryl-5-pyrazolcarbonic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-2513063-A1 | METHOD FOR PRODUCING 1-ALKYL-/1-ARYL-5-PYRAZOLE-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2012-10-24 | — | — | EP | disclosed |
| US-20110152532-A1 | Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110152532-A1 | Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110152532-A1 | Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| WO-2011073101-A1 | METHOD FOR PRODUCING 1-ALKYL-/1-ARYL-5-PYRAZOLE-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073101-A1 | METHOD FOR PRODUCING 1-ALKYL-/1-ARYL-5-PYRAZOLE-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152532-A1 | Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives | AADAC, CYP4X1, CYP4Z1 | ALDH1A1 317/4885PDE4B 636/4885HSD11B1 1852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.