SCHEMBL340847

SCHEMBL340847

COC(=O)c1cc(CO)nn1-c1ncccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 6/20 0.38
SLC16A3 O15427 1/20 0.38
SLC16A1 P53985 1/20 0.38
RBP4 P02753 1/20 0.38
ALDH1A1 P00352 2/20 0.37
DHODH Q02127 1/20 0.37
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL955031 0.96 MALT1 (0.36) MALT1SLC16A3SLC16A1RBP4ALDH1A1
Hydrochloric Acid SCHEMBL959170 0.92 SLC16A3 (0.36) MALT1SLC16A3SLC16A1RBP4DHODH
SCHEMBL2623669 0.91 MALT1 (0.39) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL30206595 0.91 MALT1 (0.38) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL421559 0.91 MALT1 (0.38) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL25008752 0.89 SLC16A3 (0.41) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL16014672 0.89 MALT1 (0.37) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL341689 0.89 DHODH (0.38) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL11928300 0.89 SLC16A3 (0.38) MALT1SLC16A3SLC16A1POLBMAPT
SCHEMBL1980280 0.88 ALDH1A1 (0.46) SLC16A3SLC16A1ALDH1A1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9609868-B2 Alkoximino-substituted anthranilic acid diamides as pesticides BAYER CROPSCIENCE AG (DE) 2017-04-04 US disclosed
US-20160007603-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2016-01-14 US disclosed
EP-2964629-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-01-13 EP disclosed
EP-2582688-B1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-10-07 EP disclosed
US-8946236-B2 Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents BAYER CROPSCIENCE AG (DE) 2015-02-03 US disclosed
WO-2014135588-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-09-12 WO disclosed
US-8791139-B2 Anthranilic diamide derivatives BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
EP-2456747-B1 Method for preparing alkoxyenones and enaminoketones BAYER CROPSCIENCE AG (DE) 2014-06-25 EP disclosed
EP-2456760-B1 Method for manufacturing aryl-substituted pyrazoles BAYER CROPSCIENCE AG (DE) 2014-05-07 EP disclosed
CN-101466702-B Anthranilic acid diamide derivatives with heteroaromatic and heterocyclic substituents BAYER CROPSCIENCE AG 2014-04-02 CN disclosed
US-20110152532-A1 Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2011-06-23 US disclosed
US-20110152532-A1 Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2011-06-23 US disclosed
US-20110152532-A1 Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2011-06-23 US disclosed
WO-2011073101-A1 METHOD FOR PRODUCING 1-ALKYL-/1-ARYL-5-PYRAZOLE-CARBOXYLIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-06-23 WO disclosed
US-20110028729-A1 Process for preparing aryl-substituted pyrazoles BAYER CROPSCIENCE AG (DE) 2011-02-03 US disclosed
US-20110021782-A1 Novel alkoxy enones and enamino ketones and a process for preparation thereof BAYER CROPSCIENCE AG (DE) 2011-01-27 US disclosed
WO-2011009552-A1 NOVEL ALKOXYENONES AND ENAMINOKETONES AND A METHOD FOR THE PRODUCTION THEREOF BAYER CROPSCIENCE AG (DE) 2011-01-27 WO disclosed
WO-2011009551-A1 PROCESS FOR PRODUCING ARYL-SUBSTITUTED PYRAZOLES BAYER CROPSCIENCE AG (DE) 2011-01-27 WO disclosed
US-20100029478-A1 ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-02-04 US disclosed
CN-101466702-A Anthranilic acid diamide derivatives with heteroaromatic and heterocyclic substituents BAYER CROPSCIENCE AG (DE) 2009-06-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160007603-A1 ALKOXIMINO-SUBSTITUTED ANTHRANILIC ACID DIAMIDES AS PESTICIDES ANTXR2, DDT, DAO MALT1 3927/4885SLC16A3 3539/4885SLC16A1 3252/4885
US-20110152532-A1 Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives AADAC, CYP4X1, CYP4Z1 MALT1 3056/4885SLC16A3 4612/4885SLC16A1 4345/4885
US-20110028729-A1 Process for preparing aryl-substituted pyrazoles WNK3, WNK2, TYR MALT1 2070/4885SLC16A3 3138/4885SLC16A1 4128/4885
US-20100029478-A1 ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS DDT, ANTXR2, QDPR MALT1 4418/4885SLC16A3 4072/4885SLC16A1 4076/4885
US-20110021782-A1 Novel alkoxy enones and enamino ketones and a process for preparation thereof AKR7A2, CYP51A1, PDK3 MALT1 3348/4885SLC16A3 4068/4885SLC16A1 4722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.