Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 6/20 | 0.56 |
| ▸ | GABBR1 | Q9UBS5 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278627 | 1.00 | GABBR2 (0.56) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL19803214 | 1.00 | GABBR2 (0.56) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL10507284 | 0.86 | GABBR2 (0.64) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL8239806 | 0.86 | ADRB2 (0.48) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL10681987 | 0.84 | GABBR2 (0.62) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL21553602 | 0.83 | GABBR2 (0.44) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL24878696 | 0.83 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL3637898 | 0.83 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL24878661 | 0.83 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL19803213 | 0.80 | ADRA2A (0.42) | GABBR2GABBR1LMNACYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015677-A1 | METHOD FOR THE RESOLUTION OF BACLOFEN SALTS | UNIVERSITE DE ROUEN (FR) | 2018-01-25 | — | — | WO | disclosed |