Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439539 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KDM4ECYP1A2L3MBTL1MAPT | |
| SCHEMBL853172 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAGLAPMP22 | |
| SCHEMBL7682920 | 0.74 | KDM4E (0.47) | ALDH1A1KDM4ELMNAGLAPMP22 | |
| SCHEMBL4273098 | 0.73 | NSD2 (0.51) | ALDH1A1KDM4ELMNAGLAPMP22 | |
| SCHEMBL29819457 | 0.71 | KDM4E (0.51) | ALDH1A1KDM4ELMNAGLAPMP22 | |
| Pterine SCHEMBL28301534 | 0.69 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAGLAPMP22 | |
| Pterine SCHEMBL64321 | 0.68 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAGLAPMP22 | |
| SCHEMBL1024549 | 0.68 | CYP1A2 (0.54) | ALDH1A1KDM4ELMNAGLAPMP22 | |
| SCHEMBL11103941 | 0.67 | KDM4E (0.37) | ALDH1A1KDM4ELMNAGLAPMP22 | |
| SCHEMBL3528784 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAGLAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110147217-A1 | METHOD AND APPARATUS FOR CANCER SCREENING | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2011-06-23 | — | — | US | claimed |
| US-6576105-B1 | Cancer monitoring and screening | TRUMAN STATE UNIVERSITY | 2003-06-10 | — | — | US | claimed |
| US-10011602-B2 | Immunological reagents and uses therefor | THE UNIVERSITY OF MELBOURNE (AU) | 2018-07-03 | — | — | US | disclosed |
| US-9207205-B2 | Method and apparatus for cancer screening | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150166542-A1 | IMMUNOLOGICAL REAGENTS AND USES THEREFOR | THE UNIVERSITY OF MELBOURNE (AU) | 2015-06-18 | — | — | US | disclosed |
| WO-2014005194-A1 | IMMUNOLOGICAL REAGENTS AND USES THEREFOR | THE UNIVERSITY OF MELBOURNE (AU) | 2014-01-09 | — | — | WO | disclosed |
| US-20110147217-A1 | METHOD AND APPARATUS FOR CANCER SCREENING | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2011-06-23 | — | — | US | disclosed |
| EP-1332207-B1 | TRANSFORMATION SYSTEMS FOR FLAVINOGENIC YEAST | ARCHER DANIELS MIDLAND CO (US) | 2008-10-29 | — | — | EP | disclosed |
| US-7009045-B2 | Transformation systems for flavinogenic yeast | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2006-03-07 | — | — | US | disclosed |
| EP-1332207-A2 | TRANSFORMATION SYSTEMS FOR FLAVINOGENIC YEAST | Abbas, Charles (US) | 2003-08-06 | — | — | EP | disclosed |
| US-6576105-B1 | Cancer monitoring and screening | TRUMAN STATE UNIVERSITY | 2003-06-10 | — | — | US | disclosed |
| WO-2000040744-A1 | METHOD FOR SCREENING FOR INHIBITORS OF RIBOFLAVIN BIOSYNTHESIS | BACHER ADELBERT (DE) | 2000-07-13 | — | — | WO | disclosed |
| WO-2000023448-A1 | NOVEL PTERIN ANTINEOPLASTIC AGENTS | MOHENO PHILLIP B B (US) | 2000-04-27 | — | — | WO | disclosed |
| US-5401844-A | Chemical intermediates for treatment of parkinson*s disease | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION (US) | 1995-03-28 | — | — | US | disclosed |
| US-5196533-A | Treatment of Parkinson*s disease, inhibitor of thymidylate synthetase | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION, USA (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0138995-B1 | REGULATION OF ENZYMES WHICH UTILIZE TETRAHYDROBIOPTERIN OR TETRAHYDROFOLATE COFACTORS WITH 6, 6-DISUBSTITUTED-TETRAHYDROPTERIDINES | South Alabama Medical Science Foundation (US) | 1991-08-14 | — | — | EP | disclosed |
| EP-0138995-A4 | REGULATION OF ENZYMES WHICH UTILIZE TETRAHYDROBIOPTERIN OR TETRAHYDROFOLATE COFACTORS WITH 6, 6-DISUBSTITUTED-TETRAHYDROPTERIDINES. | UNIV SOUTH ALABAMA (US) | 1988-05-10 | — | — | EP | disclosed |
| EP-0138995-A1 | REGULATION OF ENZYMES WHICH UTILIZE TETRAHYDROBIOPTERIN OR TETRAHYDROFOLATE COFACTORS WITH 6, 6-DISUBSTITUTED-TETRAHYDROPTERIDINES. | UNIV SOUTH ALABAMA (US) | 1985-05-02 | — | — | EP | disclosed |
| WO-1984004040-A1 | REGULATION OF ENZYMES WHICH UTILIZE TETRAHYDROBIOPTERIN OR TETRAHYDROFOLATE COFACTORS WITH 6, 6-DISUBSTITUTED-TETRAHYDROPTERIDINES | UNIV SOUTH ALABAMA (US) | 1984-10-25 | — | — | WO | disclosed |
| US-4371514-A | Radioimmunoassay of pterins and novel pterin derivatives useful therefor | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 1983-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166542-A1 | IMMUNOLOGICAL REAGENTS AND USES THEREFOR | CD81, MRGPRX1, MRGPRX2 | ALDH1A1 526/4885KDM4E 3897/4885LMNA 3717/4885 |
| US-10011602-B2 | Immunological reagents and uses therefor | CD81, MRGPRX1, MRGPRX2 | ALDH1A1 526/4885KDM4E 3897/4885LMNA 3717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.