Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pterine SCHEMBL28301534 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL7682920 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL24629541 | 0.82 | PDK2 (0.40) | ALDH1A1KDM4EPDK2PDK4HPGD | |
| SCHEMBL22497884 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL3528784 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL3526052 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL3528804 | 0.79 | MAPK1 (0.41) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL11103941 | 0.79 | KDM4E (0.37) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL398502 | 0.77 | KDM4E (0.38) | ALDH1A1KDM4EHSD17B10LMNAGLA | |
| SCHEMBL14403234 | 0.77 | NOS1 (0.40) | ALDH1A1KDM4EHSD17B10LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109946412-B | Kit for detecting spectrum of humoral pterin and use thereof | 上海产业技术研究院 | 2021-10-15 | — | — | CN | claimed |
| CN-109946412-A | A kind of body fluid pterin spectrum detection kit and its use | 上海产业技术研究院 | 2019-06-28 | — | — | CN | claimed |
| US-4758312-A | Adding colorless electrochemically active compound having positive reduction potential | NALCO CHEMICAL COMPANY (US) | 1988-07-19 | — | — | US | claimed |
| EP-3554479-B1 | A METHOD FOR PRODUCING BEADS | AGRICULTURE AND FOOD DEV AUTHORITY TEAGASC (IE) | 2022-02-16 | — | — | EP | disclosed |
| CN-109946412-B | Kit for detecting spectrum of humoral pterin and use thereof | 上海产业技术研究院 | 2021-10-15 | — | — | CN | disclosed |
| US-20200276127-A1 | METHOD FOR PRODUCING BEADS | AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (IE) | 2020-09-03 | — | — | US | disclosed |
| EP-3554479-A1 | A METHOD FOR PRODUCING BEADS | Agriculture and Food Development Authority (TEAGASC) (IE) | 2019-10-23 | — | — | EP | disclosed |
| CN-109946412-A | A kind of body fluid pterin spectrum detection kit and its use | 上海产业技术研究院 | 2019-06-28 | — | — | CN | disclosed |
| WO-2018114971-A1 | A METHOD FOR PRODUCING BEADS | AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (IE) | 2018-06-28 | — | — | WO | disclosed |
| EP-2432314-B1 | MOUSE MODELS CARRYING A KNOCK-OUT MUTATION OF THE QPCTL-GENE | PROBIODRUG AG (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-20160368944-A1 | LINKED PURINE PTERIN HPPK INHIBITORS USEFUL AS ANTIBACTERIAL AGENTS | US HEALTH (US) | 2016-12-22 | — | — | US | disclosed |
| WO-2001000842-A2 | CORYNEBACTERIUM GLUTAMICUM GENES ENCODING PROTEINS INVOLVED IN HOMEOSTASIS AND ADAPTATION | BASF AKTIENGESELLSCHAFT (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000844-A2 | CORYNEBACTERIUM GLUTAMICUM GENES ENCODING PROTEINS INVOLVED IN CARBON METABOLISM AND ENERGY PRODUCTION | BASF AKTIENGESELLSCHAFT (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000804-A2 | CORYNEBACTERIUM GLUTAMICUM GENES ENCODING STRESS, RESISTANCE AND TOLERANCE PROTEINS | BASF AKTIENGESELLSCHAFT (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000004163-A9 | TETRAHYDROFOLATE METABOLISM ENZYMES | DU PONT (US) | 2000-07-20 | — | — | WO | disclosed |
| WO-2000023448-A1 | NOVEL PTERIN ANTINEOPLASTIC AGENTS | MOHENO PHILLIP B B (US) | 2000-04-27 | — | — | WO | disclosed |
| WO-2000004163-A1 | TETRAHYDROFOLATE METABOLISM ENZYMES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-01-27 | — | — | WO | disclosed |
| US-4758312-A | Adding colorless electrochemically active compound having positive reduction potential | NALCO CHEMICAL COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0237738-A2 | Method for in situ corrosion detection using electrochemically active compounds | NALCO CHEMICAL COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| US-4683035-A | Method for in situ corrosion detection using electrochemically active compounds | NALCO CHEMICAL COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368944-A1 | LINKED PURINE PTERIN HPPK INHIBITORS USEFUL AS ANTIBACTERIAL AGENTS | PDXK, HPRT1, PLPBP | ALDH1A1 3443/4885KDM4E 3953/4885HSD17B10 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.