Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18026356 | 0.83 | DGAT1 (0.37) | DGAT1TSHRALDH1A1POLB | |
| SCHEMBL8037849 | 0.82 | DGAT1 (0.33) | DGAT1TSHR | |
| SCHEMBL23628722 | 0.73 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL27879936 | 0.71 | KDM5A (0.39) | POLB | |
| SCHEMBL22874332 | 0.70 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL22874325 | 0.70 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL7048475 | 0.69 | MMP1 (0.31) | DGAT1 | |
| SCHEMBL26998813 | 0.69 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL2475483 | 0.69 | DGAT1 (0.44) | DGAT1TSHRALDH1A1POLB | |
| SCHEMBL5613238 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021336-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | AUTIFONY THERAPEUTICS LIMITED (GB) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021336-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | KCND3, KCNK3, KCNA3 | DGAT1 4172/4885TSHR 1840/4885ALDH1A1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.