Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805314 | 0.82 | DGAT1 (0.34) | DGAT1TSHR | |
| SCHEMBL2871889 | 0.71 | TSHR (0.43) | DGAT1TSHRHSD17B10 | |
| SCHEMBL2879624 | 0.69 | — | — | |
| SCHEMBL18026356 | 0.68 | DGAT1 (0.37) | DGAT1TSHR | |
| SCHEMBL22874325 | 0.68 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL22874332 | 0.68 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL9207406 | 0.67 | — | — | |
| SCHEMBL18534253 | 0.67 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL15827293 | 0.67 | TSHR (0.36) | DGAT1TSHRHSD17B10 | |
| SCHEMBL24652059 | 0.66 | TSHR (0.39) | DGAT1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105284-A1 | METHODS OF PREPARATION OF MACROCYCLIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-08-27 | — | — | WO | disclosed |