Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324389 | 0.82 | HTR7 (0.58) | ALDH1A1KDM4EMITFHTTACHE | |
| SCHEMBL19806074 | 0.80 | HTR2A (0.40) | ALDH1A1PPARGPPARDPPARATUBB1 | |
| SCHEMBL3436226 | 0.79 | HTT (0.52) | ALDH1A1KDM4EMITFHTTACHE | |
| SCHEMBL22912199 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EMITFHTTACHE | |
| SCHEMBL8481621 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4EHTTPPARGPPARD | |
| SCHEMBL19936609 | 0.76 | KDM4E (0.50) | ALDH1A1KDM4EMITFHTTACHE | |
| SCHEMBL8327653 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KDM4EMITFHTTACHE | |
| SCHEMBL14340525 | 0.75 | KDM4E (0.52) | ALDH1A1KDM4EMITFHTTACHE | |
| SCHEMBL186570 | 0.74 | HTT (0.50) | ALDH1A1KDM4EMITFHTTCYP17A1 | |
| SCHEMBL9135638 | 0.74 | CYP17A1 (0.49) | ALDH1A1KDM4EMITFHTTCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |