Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805921 | 0.80 | ALDH1A1 (0.49) | ALDH1A1PPARGPPARDPPARATUBB1 | |
| SCHEMBL19806072 | 0.74 | ALDH1A1 (0.43) | HTR2AHTR2CHTR2BPTGS2LMNA | |
| SCHEMBL29976346 | 0.72 | HTR2A (0.48) | HTR2AHTR2CHTR2BAOC3PTGS2 | |
| SCHEMBL19806073 | 0.72 | HTR2A (0.48) | HTR2AHTR2CHTR2BAOC3PTGS2 | |
| SCHEMBL7283121 | 0.72 | HTR2A (0.48) | HTR2AHTR2CHTR2BPTGS2MAPT | |
| SCHEMBL24452088 | 0.71 | IDO1 (0.34) | — | |
| SCHEMBL1159408 | 0.70 | HTR2A (0.79) | HTR2AHTR2CHTR2BAOC3PTGS2 | |
| Hydrochloric Acid SCHEMBL7283025 | 0.69 | HTR2A (0.76) | HTR2AHTR2CHTR2BAOC3PTGS2 | |
| SCHEMBL19197756 | 0.69 | PTGS2 (0.59) | HTR2AHTR2CHTR2BAOC3PTGS2 | |
| SCHEMBL7283120 | 0.68 | HTR2A (0.44) | HTR2AHTR2CHTR2BAOC3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |