Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12522638 | 0.92 | SIGMAR1 (0.45) | SIGMAR1ACHECYP1A2L3MBTL1 | |
| SCHEMBL12522639 | 0.92 | SIGMAR1 (0.45) | SIGMAR1ACHECYP1A2L3MBTL1 | |
| SCHEMBL12950 | 0.84 | KDM4E (0.47) | SIGMAR1ACHECYP1A2L3MBTL1CHRM5 | |
| SCHEMBL12449662 | 0.84 | KDM4E (0.47) | SIGMAR1ACHECYP1A2L3MBTL1CHRM5 | |
| SCHEMBL17828184 | 0.81 | ACHE (0.64) | SIGMAR1ACHECYP1A2L3MBTL1CHRM5 | |
| SCHEMBL18082890 | 0.79 | GBA1 (0.37) | SIGMAR1 | |
| SCHEMBL26243578 | 0.78 | SIGMAR1 (0.44) | SIGMAR1CYP1A2L3MBTL1 | |
| SCHEMBL11850078 | 0.77 | CYP1A2 (0.48) | SIGMAR1ACHECYP1A2CHRM5ADRA2C | |
| SCHEMBL6047959 | 0.77 | SIGMAR1 (0.44) | SIGMAR1ACHECYP1A2L3MBTL1CHRM5 | |
| SCHEMBL25690948 | 0.76 | NCF1 (0.41) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |