Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806332 | 0.80 | HDAC4 (0.34) | MAPTHSD17B10NPC1ALDH1A1TP53 | |
| SCHEMBL21220122 | 0.78 | HSD17B10 (0.39) | MAPTHSD17B10NPC1ALDH1A1TP53 | |
| SCHEMBL29475165 | 0.78 | HSD17B10 (0.39) | MAPTHSD17B10NPC1ALDH1A1TP53 | |
| SCHEMBL19806262 | 0.72 | NMT2 (0.38) | MAPTHSD17B10NPC1ALDH1A1TP53 | |
| SCHEMBL23198438 | 0.70 | CA1 (0.31) | NPC1MAPK1 | |
| SCHEMBL29860611 | 0.69 | MAPT (0.44) | ADORA1MAPTALDH1A1XBP1MAPK1 | |
| SCHEMBL21749970 | 0.69 | MAPT (0.44) | ADORA1MAPTALDH1A1XBP1MAPK1 | |
| SCHEMBL7488806 | 0.68 | CDC7 (0.47) | ADORA1MAPTHSD17B10NPC1ALDH1A1 | |
| SCHEMBL3866652 | 0.67 | BRD4 (0.49) | ADORA1MAPTNPC1ALDH1A1HTT | |
| SCHEMBL30641368 | 0.67 | SMN1; SMN2 (0.41) | ADORA1MAPTALDH1A1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689662-B | Fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2022-03-15 | — | — | CN | disclosed |
| EP-3487860-B1 | CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-18 | — | — | US | disclosed |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-18 | — | — | US | disclosed |
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-08 | — | — | US | disclosed |
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-08 | — | — | US | disclosed |
| WO-2018015289-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, ACHE, BCHE | ADORA1 126/4885MAPT 2049/4885HSD17B10 652/4885 |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, ACHE, BCHE | ADORA1 126/4885MAPT 2049/4885HSD17B10 652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.