Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | ILK | Q13418 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475165 | 1.00 | HSD17B10 (0.39) | HSD17B10HPGDKDM4EPKMBRD4 | |
| SCHEMBL19806262 | 0.81 | NMT2 (0.38) | HSD17B10HPGDKDM4EPKMBRD4 | |
| SCHEMBL2880659 | 0.79 | ALDH1A1 (0.41) | HSD17B10KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL19806331 | 0.78 | ADORA1 (0.40) | HSD17B10HPGDKDM4EPKMALDH1A1 | |
| SCHEMBL19806332 | 0.76 | HDAC4 (0.34) | HSD17B10HPGDKDM4EPKMALDH1A1 | |
| SCHEMBL2960289 | 0.75 | EGLN1 (0.32) | KDM4EALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL2881009 | 0.75 | ALDH1A1 (0.39) | HSD17B10HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL2880509 | 0.72 | KDM4E (0.57) | HPGDKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL2880781 | 0.72 | CDC7 (0.56) | HSD17B10PKMALDH1A1MAPTNPC1 | |
| SCHEMBL2884453 | 0.72 | CDC7 (0.41) | ALDH1A1MAPTCYP1A2CDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487860-B1 | CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-18 | — | — | US | disclosed |
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, ACHE, BCHE | HSD17B10 652/4885HPGD 1420/4885KDM4E 2452/4885 |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, ACHE, BCHE | HSD17B10 652/4885HPGD 1420/4885KDM4E 2452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.