Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18012494 | 1.00 | CYP1A2 (0.59) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL21322442 | 1.00 | CYP1A2 (0.59) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7351208 | 1.00 | CYP1A2 (0.59) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL30702633 | 1.00 | CYP1A2 (0.59) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1012062 | 1.00 | CYP1A2 (0.59) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7351213 | 1.00 | CYP1A2 (0.59) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1012152 | 1.00 | CYP1A2 (0.59) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29352680 | 0.98 | CYP1A2 (0.58) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8108146 | 0.84 | CYP1A2 (0.42) | CYP1A2HIF1ASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL10243319 | 0.81 | CYP1A2 (0.40) | CYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022756-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | FRED HUTCHINSON CANCER CENTER | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022756-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | CASP3, AIFM1, ATP6V1B1 | CYP1A2 4708/4885HIF1A 2401/4885SLC6A3 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.