SCHEMBL19809268

SCHEMBL19809268

Nc1cc(-c2c(OC(=O)c3ccccc3)ccc(O)c2N)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.46
▸ MAPT P10636 4/20 0.46
▸ MEN1 O00255 4/20 0.46
▸ USP2 O75604 2/20 0.46
▸ GAA P10253 2/20 0.46
▸ ALOX15 P16050 2/20 0.46
▸ HSD17B10 Q99714 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ HSP90AA1 P07900 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ ALOX12 P18054 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ ESR1 P03372 2/20 0.43
▸ ESR2 Q92731 2/20 0.43
▸ JAK2 O60674 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ SERPINE1 P05121 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809269 0.91 KMT2A (0.42) KMT2AMAPTMEN1USP2GAA
SCHEMBL19809453 0.88 KMT2A (0.45) KMT2AMAPTMEN1USP2GAA
SCHEMBL19809404 0.79 SERPINE1 (0.43) KMT2AMAPTMEN1USP2GAA
SCHEMBL14859395 0.74 KMT2A (0.60) KMT2AMAPTMEN1GAAHSD17B10
SCHEMBL28260589 0.71 SMN1; SMN2 (0.41) KMT2AMAPTMEN1USP2GAA
SCHEMBL17783723 0.71 KMO (0.43) KMT2AMAPTMEN1USP2GAA
SCHEMBL14615844 0.70 HSD17B1 (0.50) KMT2AMAPTMEN1USP2GAA
SCHEMBL27639137 0.69 KMT2A (0.51) KMT2AMAPTMEN1USP2GAA
SCHEMBL10633834 0.69 KMT2A (0.59) KMT2AMAPTMEN1USP2GAA
SCHEMBL9744231 0.69 MAPT (0.56) KMT2AMAPTMEN1USP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10696845-B2 Energy-sensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 2020-06-30 — — US disclosed
EP-3275940-B1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO LTD (JP) 2019-12-18 — — EP disclosed
US-20190225804-A1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2019-07-25 — — US disclosed
EP-3275940-A1 ENERGY-SENSITIVE RESIN COMPOSITION Tokyo Ohka Kogyo Co., Ltd. (JP) 2018-01-31 — — EP disclosed
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