Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19809984 | 1.00 | LMNA (0.41) | LMNAKDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL18229666 | 0.89 | ALDH1A1 (0.36) | LMNAKDM4EKMT2AMEN1SLC13A5 | |
| SCHEMBL18229667 | 0.89 | ALDH1A1 (0.36) | LMNAKDM4EKMT2AMEN1SLC13A5 | |
| SCHEMBL19831915 | 0.82 | ALDH1A1 (0.34) | KMT2AALDH1A1CYP2C19HIF1ASLC6A2 | |
| SCHEMBL18229734 | 0.82 | LMNA (0.33) | LMNAKDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL18229702 | 0.82 | LMNA (0.33) | LMNAKDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL19810006 | 0.81 | MEN1 (0.39) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL19810007 | 0.81 | MEN1 (0.39) | LMNAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL18229656 | 0.74 | ALDH1A1 (0.38) | LMNAKDM4ECYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL20156625 | 0.74 | SLC13A5 (0.32) | LMNAKDM4EKMT2AMEN1SLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018019549-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.P.A. (IT) | 2018-02-01 | — | — | WO | claimed |
| EP-3275875-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.p.A. (IT) | 2018-01-31 | — | — | EP | claimed |
| WO-2018019549-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.P.A. (IT) | 2018-02-01 | — | — | WO | disclosed |
| EP-3275875-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.p.A. (IT) | 2018-01-31 | — | — | EP | disclosed |