Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19810007 | 1.00 | MEN1 (0.39) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL18229667 | 0.92 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL18229666 | 0.92 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL19829243 | 0.89 | MEN1 (0.37) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL18229652 | 0.87 | MEN1 (0.33) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL18229654 | 0.87 | MEN1 (0.33) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL19809983 | 0.81 | LMNA (0.41) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL19809984 | 0.81 | LMNA (0.41) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL17200135 | 0.77 | PTPN1 (0.46) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL18229734 | 0.76 | LMNA (0.33) | MEN1KMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018019549-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.P.A. (IT) | 2018-02-01 | — | — | WO | claimed |
| EP-3275875-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.p.A. (IT) | 2018-01-31 | — | — | EP | claimed |
| WO-2018019549-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.P.A. (IT) | 2018-02-01 | — | — | WO | disclosed |
| EP-3275875-A1 | DIOXOLANONE INTERMEDIATE USEFUL IN THE SYNTHESIS OF HOMOHARRINGTONINE | INDENA S.p.A. (IT) | 2018-01-31 | — | — | EP | disclosed |