Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391523 | 1.00 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL395418 | 1.00 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| Ethyl Acetate SCHEMBL27915037 | 0.93 | ALDH1A1 (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL29980213 | 0.91 | MGAM (0.38) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL29133365 | 0.86 | GAA (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6155363 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AHSD17B10LMNA | |
| SCHEMBL15233366 | 0.82 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8798167 | 0.82 | NAAA (0.42) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL6155660 | 0.82 | NAAA (0.42) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL6931390 | 0.81 | TSHR (0.36) | ALDH1A1MEN1KMT2ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-221062625-U | Adding device for sulfuric acid and sodium cyanide in production of R-4-cyano-3-hydroxybutyric acid ethyl ester | 江苏万年长药业有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-116904530-A | Biological preparation method of atorvastatin calcium intermediate | 江苏福瑞康泰药业有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116718704-A | Method for detecting enantiomer of R-4-cyano-3-hydroxybutyric acid ethyl ester | 抚顺顺能化工有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-116254303-A | Enzyme treatment method in production process of R-4-cyano-3-hydroxybutyric acid ethyl ester | 江苏万年长药业有限公司 | 2023-06-13 | — | — | CN | claimed |
| CN-112430197-B | Synthesis method of 3-oxo-5-hydroxy-6-cyano tert-butyl caproate | 江苏阿尔法药业股份有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-115894290-A | Preparation method of atorvastatin calcium intermediate (R) - (-) -4-cyano-3-hydroxy ethyl butyrate | 宿迁阿尔法科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-216727181-U | Esterification reaction system in production process of R-4-cyano-3-hydroxy ethyl butyrate | 江苏万年长药业有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-214609343-U | Storage device for preparing ethyl 4-cyano-3-hydroxybutyrate | 温州市嘉力化工有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-214539514-U | Sample detection device for preparing 4-cyano-3-hydroxy ethyl butyrate | 温州市嘉力化工有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-214422651-U | Equipment for producing (R) -4-cyano-3-hydroxy ethyl butyrate | 江苏阿尔法药业股份有限公司 | 2021-10-19 | — | — | CN | claimed |
| CN-101914582-A | Organism coupling preparation method of R(-)-4-cyan-3-hydroxybutyric acid ethyl ester | LIANYUNGANG HONGYE CHEMICAL CO LTD | 2010-12-15 | — | — | CN | claimed |
| US-7811804-B2 | synthetic or recombinant polypeptide having a nitrilase activity; have increased activity and stability at increased pH and temperature | VERENIUM CORPORATION (US) | 2010-10-12 | — | — | US | claimed |
| US-20100216214-A1 | hydrolysis of a hydroxyglutaryl nitrile to generate an ethyl 4-cyano-3-hydroxybutyrate; hydrolysis of a mandelonitrile to generate a mandelic acid; hydrolysis of phenyllactocyanonitrile to generate an (S)-phenyllactic acid | VERENIUM CORPORATION (US) | 2010-08-26 | — | — | US | claimed |
| EP-2039762-A2 | Nitralases | Verenium Corporation (US) | 2009-03-25 | — | — | EP | claimed |
| CN-101260415-A | Preparation of two kinds of high optical activity enantiomer of ethyl 4-cyano-3-hydroxybutyrate by biological catalysis method | APPLIC CHEMISTRY SUBCT OF JIAX (CN) | 2008-09-10 | — | — | CN | claimed |
| EP-1551796-A4 | IMPROVED SYNTHETON SYNTHESIS | SK ENERGY AND CHEMICAL INC (US) | 2007-03-14 | — | — | EP | claimed |
| EP-1551796-A1 | IMPROVED SYNTHETON SYNTHESIS | SK Energy and Chemical, Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| WO-2004031131-A1 | IMPROVED SYNTHETON SYNTHESIS | SK ENERGY AND CHEMICAL INC. (US) | 2004-04-15 | — | — | WO | claimed |
| US-20040053378-A1 | Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid | DIVERSA CORPORATION (US) | 2004-03-18 | — | — | US | claimed |
| WO-2003106415-A2 | PROCESSES FOR MAKING (R)-ETHYL 4-CYANO-3-HYDROXYBUTYRIC ACID | DIVERSA CORPORATION (US) | 2003-12-24 | — | — | WO | claimed |