SCHEMBL19815096

SCHEMBL19815096

O=C(O)N1CCC(=O)C2(CCC2)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.31
DDB1 Q16531 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19815033 0.96 CRBN (0.31) CRBNDDB1
SCHEMBL19815023 0.95 KMT2A (0.33) CRBNDDB1
SCHEMBL2159192 0.92 CRBN (0.33) CRBNDDB1
SCHEMBL19817308 0.84 ALDH1A1 (0.34)
SCHEMBL17112824 0.79 DDB1 (0.30) CRBNDDB1
SCHEMBL17611698 0.78 CRBN (0.40) CRBNDDB1
SCHEMBL21197226 0.76 USP30 (0.44) CRBNDDB1
SCHEMBL5895840 0.76 SPR (0.35) CRBNDDB1
SCHEMBL18321890 0.74 SPR (0.36) CRBNDDB1
SCHEMBL505075 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3490982-B1 PHARMACEUTICAL COMPOUNDS ALMAC DISCOVERY LTD (GB) 2022-04-20 EP disclosed
US-20220002264-A1 PHARMACEUTICAL COMPOUNDS ALMAC DISCOVERY LIMITED (GB) 2022-01-06 US disclosed
US-11053213-B2 Pharmaceutical compounds ALMAC DISCOVERY LIMITED (GB) 2021-07-06 US disclosed
US-20190233394-A1 PHARMACEUTICAL COMPOUNDS ALMAC DISCOVERY LIMITED (GB) 2019-08-01 US disclosed
EP-3490982-A1 PHARMACEUTICAL COMPOUNDS Almac Discovery Limited (GB) 2019-06-05 EP disclosed
WO-2018020242-A1 PHARMACEUTICAL COMPOUNDS ALMAC DISCOVERY LIMITED (GB) 2018-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190233394-A1 PHARMACEUTICAL COMPOUNDS USP19, USP18, UBE2I CRBN 422/4885DDB1 2736/4885
US-20220002264-A1 PHARMACEUTICAL COMPOUNDS USP19, USP18, UBE2I CRBN 422/4885DDB1 2736/4885
US-11053213-B2 Pharmaceutical compounds USP19, USP18, UBE2I CRBN 422/4885DDB1 2736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.