Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19815197 | 0.83 | BACE1 (0.50) | BACE1THRBALOX12KMT2APORCN | |
| SCHEMBL21050341 | 0.81 | BACE1 (0.43) | BACE1THRBALOX12KMT2AL3MBTL1 | |
| SCHEMBL3047808 | 0.78 | SCN9A (0.49) | BACE1THRBALOX12KMT2AALDH1A1 | |
| SCHEMBL9891645 | 0.72 | NOTUM (0.53) | THRBALOX12KMT2AALDH1A1NOTUM | |
| SCHEMBL20458161 | 0.72 | NOTUM (0.53) | THRBALOX12KMT2AALDH1A1NOTUM | |
| SCHEMBL21660770 | 0.72 | EGLN1 (0.43) | BACE1ALDH1A1NOTUM | |
| SCHEMBL2172455 | 0.71 | SCN9A (0.60) | — | |
| SCHEMBL28690247 | 0.71 | CASP3 (0.41) | BACE1THRBALOX12KMT2ACNR2 | |
| SCHEMBL25262222 | 0.71 | TDP1 (0.45) | THRBALOX12KMT2APORCNALDH1A1 | |
| Hydrochloric Acid SCHEMBL2169819 | 0.70 | SCN9A (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3490984-A1 | 2-PYRROLIDINE PHENYLHYDRAZIDES ANTIBACTERIAL AGENTS | Abac Therapeutics, S.L (ES) | 2019-06-05 | — | — | EP | disclosed |
| WO-2018020004-A1 | 2-PYRROLIDINE PHENYLHYDRAZIDES ANTIBACTERIAL AGENTS | ABAC THERAPEUTICS, S.L (ES) | 2018-02-01 | — | — | WO | disclosed |