Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12041041 | 0.98 | DPP4 (0.54) | DPP4DRD2SIGMAR1GRM2CHRNA7 | |
| SCHEMBL12041166 | 0.98 | DPP4 (0.54) | DPP4DRD2SIGMAR1GRM2CHRNA7 | |
| SCHEMBL15037944 | 0.95 | DPP4 (0.60) | DPP4DRD2SIGMAR1GRM2CHRNA7 | |
| SCHEMBL12041249 | 0.82 | CHRNA7 (0.59) | DRD2SIGMAR1CHRNA7HRH3KCNH2 | |
| SCHEMBL2095327 | 0.81 | SLC6A2 (0.47) | DPP4DRD2CHRNA7HRH3KCNH2 | |
| SCHEMBL3389633 | 0.81 | CYP2D6 (0.56) | DPP4DRD2HRH3KCNH2SLC6A2 | |
| SCHEMBL16202806 | 0.81 | MAPT (0.48) | DPP4DRD2CHRNA7HRH3SLC6A2 | |
| SCHEMBL424881 | 0.80 | CHRNA7 (0.55) | DPP4DRD2SIGMAR1CHRNA7HRH3 | |
| SCHEMBL25192949 | 0.79 | MAPT (0.51) | DPP4GRM2HRH3L3MBTL1 | |
| SCHEMBL30516679 | 0.79 | KDM4E (0.44) | DPP4HRH3L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241436-B2 | Autophagy inducers for treatment of CNS conditions | NORTHWESTERN UNIVERSITY (US) | 2022-02-08 | — | — | US | disclosed |
| US-9877966-B1 | Combination therapy for the inhibition of metastasis and tumorigenesis | OLIVA EUGENE J (US) | 2018-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11241436-B2 | Autophagy inducers for treatment of CNS conditions | SQSTM1, ATG7, BECN1 | DPP4 4434/4885DRD2 1385/4885SIGMAR1 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.