Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 3/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615779 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL15880035 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL28575467 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL11512199 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL7568504 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL8588942 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL11316935 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL19040769 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL19821297 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA | |
| SCHEMBL11317527 | 1.00 | TSHR (0.54) | TSHRTDP1ALOX15KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | TSHR 3374/4885TDP1 753/4885ALOX15 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.