SCHEMBL8588942

SCHEMBL8588942

CCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCC)CC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.54
TDP1 Q9NUW8 4/20 0.54
ALOX15 P16050 2/20 0.54
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
CHRM2 P08172 1/20 0.54
ADRA2A P08913 1/20 0.54
DRD1 P21728 1/20 0.54
SLC6A2 P23975 1/20 0.54
SLC6A4 P31645 1/20 0.54
CYP2C19 P33261 1/20 0.54
ADRA1A P35348 1/20 0.54
DRD3 P35462 1/20 0.54
BLM P54132 1/20 0.54
PMP22 Q01453 1/20 0.54
SLC6A3 Q01959 1/20 0.54
HRH3 Q9Y5N1 1/20 0.54
KDM5A P29375 3/20 0.51
PHF8 Q9UPP1 2/20 0.51
KDM4C Q9H3R0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615779 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL15880035 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL28575467 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL11512199 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL7568504 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL11316935 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL19040769 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL19821297 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL19821298 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA
SCHEMBL11317527 1.00 TSHR (0.54) TSHRTDP1ALOX15KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120026189-A Hydrophobic aminocarboxylic acid coordination system for comprehensively utilizing titanium, zirconium and hafnium by minerals 山东金鸾科技开发有限公司 2025-05-23 CN disclosed
CN-118580291-A Antiviral prodrugs and formulations thereof 斯克里普斯研究所 2024-09-03 CN disclosed
CN-114929236-B Antiviral prodrugs and formulations thereof 斯克里普斯研究所 2024-06-07 CN disclosed
US-20220323476-A1 ANTIVIRAL PRODRUGS AND FORMULATIONS THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-10-13 US disclosed
EP-4028020-A1 ANTIVIRAL PRODRUGS AND FORMULATIONS THEREOF The Scripps Research Institute (US) 2022-07-20 EP disclosed
US-20180028664-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2018-02-01 US disclosed
WO-1998050078-A1 LIPOPHILIC AND/OR LYTIC PEPTIDES FOR SPECIFIC DELIVERY OF NUCLEIC ACIDS TO CELLS GENEMEDICINE, INC. (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220323476-A1 ANTIVIRAL PRODRUGS AND FORMULATIONS THEREOF PNP, ADA, ENTPD5 TSHR 4618/4885TDP1 429/4885ALOX15 1018/4885
US-20180028664-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 TSHR 3374/4885TDP1 753/4885ALOX15 2829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.