SCHEMBL78614

SCHEMBL78614

O=C(O)c1ccc(Br)c(Br)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.52
SELP P16109 1/20 0.52
ERN1 O75460 2/20 0.47
AKR1C4 P17516 2/20 0.47
AKR1C3 P42330 2/20 0.47
AKR1C2 P52895 2/20 0.47
AKR1C1 Q04828 2/20 0.47
CYP1A2 P05177 1/20 0.44
LDHA P00338 1/20 0.44
PTPN1 P18031 4/20 0.43
PTPN2 P17706 1/20 0.43
PTPN6 P29350 1/20 0.43
ALDH1A1 P00352 2/20 0.42
ALB P02768 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MMP2 P08253 1/20 0.42
TTR P02766 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31616194 0.89 ERN1 (0.44) SELLSELPERN1AKR1C4AKR1C3
SCHEMBL1982182 0.84 SELL (0.60) SELLSELPERN1AKR1C4AKR1C3
SCHEMBL15524371 0.82 SELL (0.64) SELLSELPAKR1C4AKR1C3AKR1C2
SCHEMBL6508228 0.82 AKR1C3 (0.47) SELLSELPERN1AKR1C4AKR1C3
SCHEMBL607237 0.81 CYP1A2 (0.48) SELLSELPERN1AKR1C4AKR1C3
SCHEMBL31700545 0.80 ERN1 (0.61) ERN1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL29045172 0.79 CYP1A2 (0.46) SELLSELPERN1AKR1C4AKR1C3
SCHEMBL6887635 0.78 SELL (0.48) SELLSELPERN1AKR1C4AKR1C3
SCHEMBL14690903 0.78 ERN1 (0.38) SELLSELPERN1AKR1C4AKR1C3
SCHEMBL20505208 0.78 ALB (0.48) SELLSELPERN1AKR1C4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2524763-B1 SOLDER PASTE ARAKAWA CHEM IND (JP) 2018-12-05 EP claimed
EP-2742091-B1 THE USE OF ALUMINIUM DIBROMOSALICYLATE, A PROCESS FOR PREPARING NON-FLAMMABLE ORGANIC PLASTICS, AND A FLAME RETARDANT COMPOSITION FOR ITS PREPARATION Synthos Sa (PL) 2015-11-04 EP claimed
CN-102770233-B Solder paste ARAKAWA CHEM IND 2015-03-11 CN claimed
CN-103838086-A Composition containing reaction product of isocyanuric acid compound and benzoic acid compound for forming anti-reflection film NISSAN CHEMICAL IND LTD 2014-06-04 CN claimed
EP-1332167-B1 PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE GEN ELECTRIC (US) 2008-09-17 EP claimed
CN-101168565-A Nitric oxide-blocked cross-linked tetrameric hemoglobin IKOR INC (US) 2008-04-30 CN claimed
EP-1018525-B1 Process for preparing polyurethane foam GEN ELECTRIC (US) 2006-08-30 EP claimed
EP-1362073-B1 PROCESS TO ENHANCE POLYURETHANE FOAM PERFORMANCE GEN ELECTRIC (US) 2005-12-14 EP claimed
EP-1534766-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2005-06-01 EP claimed
CN-1198862-C Process for producing polyurethane foam plastics CK THE WHITAKER CORP (US) 2005-04-27 CN claimed
US-6395796-B1 CONDENSATION OF POLYISOCYANATE AND POLYOL USING DELAYED ACTION AMINE CATALYST FORMED BY REACTION OF HALOCARBOXYLIC ACID AND TERTIARY AMINE CROMPTON CORPORATION 2002-05-28 US claimed
US-6387972-B1 MIXTURE CONTAINING TERTIARY AMINE ADJUVANT CROMPTON CORPORATION 2002-05-14 US claimed
CN-1269372-A Process for producing polyurethane foam plastics CK THE WHITAKER CORP (US) 2000-10-11 CN claimed
EP-1018525-A1 Process for preparing polyurethane foam CK WITCO CORPORATION (US) 2000-07-12 EP claimed
US-5962651-A Modified hemoglobin and its use as a component of an artificial blood substitute MONTEFIORE MEDICAL CENTER (US) 1999-10-05 US claimed
US-5322659-A Anticlotting the medical tubes by complexing the quaternary ammonium salt in the lamination layer with a reagent solution consisting of an anticoagulants heparin, an antiinfection agents BECTON, DICKINSON AND COMPANY (US) 1994-06-21 US claimed
EP-0587610-A1 SPECIFICALLY BETA-BETA CROSS-LINKED HEMOGLOBINS AND METHOD OF PREPARATION THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1994-03-23 EP claimed
US-5250665-A Artificial blood THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1993-10-05 US claimed
WO-1992021702-A1 SPECIFICALLY BETA-BETA CROSS-LINKED HEMOGLOBINS AND METHOD OF PREPARATION THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1992-12-10 WO claimed
US-5013866-A Pharmaceutical grade 3,5-dibromosalicylic acid and metohd for synthesizing same BAXTER INTERNATIONAL INC. (US) 1991-05-07 US claimed