Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095138 | 0.80 | PELI1 (0.54) | PELI1MAPTALDH1A1KDM4EMEN1 | |
| Water SCHEMBL11694970 | 0.80 | ALDH1A1 (0.60) | PELI1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL6095141 | 0.80 | PELI1 (0.54) | PELI1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL19813877 | 0.79 | ERN1 (0.56) | PELI1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL13636232 | 0.79 | ERN1 (0.56) | PELI1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL30353437 | 0.79 | ERN1 (0.56) | PELI1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL13764832 | 0.74 | TTR (0.58) | MAPTALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL1608290 | 0.73 | NFKB1 (0.70) | MAPTKDM4ENFKB1JUNNFE2L2 | |
| SCHEMBL765999 | 0.73 | NFKB1 (0.70) | MAPTKDM4ENFKB1JUNNFE2L2 | |
| SCHEMBL8687395 | 0.73 | NFKB1 (0.70) | MAPTKDM4ENFKB1JUNNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018018091-A1 | COMPOSITIONS FOR THE TREATMENT OF PULMONARY FIBROSIS | VECTUS BIOSYSTEMS LIMITED (AU) | 2018-02-01 | — | — | WO | disclosed |