SCHEMBL765999

SCHEMBL765999

NC(=O)/C=C/c1ccccc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.70
JUN P05412 1/20 0.70
NFE2L2 Q16236 1/20 0.70
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68
CA4 P22748 1/20 0.68
MAPT P10636 3/20 0.66
LMNA P02545 1/20 0.66
BCHE P06276 1/20 0.61
GUSB P08236 1/20 0.61
CHRNA7 P36544 3/20 0.56
MAPK1 P28482 2/20 0.54
CDK4 P11802 1/20 0.53
CCND1 P24385 1/20 0.53
ALPL P05186 1/20 0.53
ALPI P09923 1/20 0.53
ALPG P10696 1/20 0.53
KDM4E B2RXH2 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1608290 1.00 NFKB1 (0.70) NFKB1JUNNFE2L2CA1CA2
SCHEMBL8687395 1.00 NFKB1 (0.70) NFKB1JUNNFE2L2CA1CA2
SCHEMBL29625452 1.00 NFKB1 (0.70) NFKB1JUNNFE2L2CA1CA2
SCHEMBL766000 1.00 NFKB1 (0.70) NFKB1JUNNFE2L2CA1CA2
SCHEMBL11406934 0.98 NFKB1 (0.68) NFKB1JUNNFE2L2CA1CA2
SCHEMBL2328371 0.87 NFKB1 (0.50) NFKB1JUNNFE2L2CA1CA2
SCHEMBL5465666 0.84 IAPP (0.68) NFKB1JUNNFE2L2CA1CA2
SCHEMBL1160535 0.83 NFKB1 (1.00) NFKB1JUNNFE2L2CA1CA2
SCHEMBL29539991 0.83 NFKB1 (1.00) NFKB1JUNNFE2L2CA1CA2
SCHEMBL1160537 0.83 NFKB1 (1.00) NFKB1JUNNFE2L2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132413-A1 AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RES FOUNDATION (US) 2026-05-14 US claimed
US-20250136952-A1 ENGINEERED PREPHENATE DEHYDROGENASES AND AROGENATE DEHYDROGENASES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RESEARCH FOUNDATION 2025-05-01 US claimed
CN-116064608-B Hordeum vulgare agmatine coumaroyl transferase gene HvACT2 and application thereof in improving disease resistance of barley 浙江大学 2025-01-28 CN claimed
US-12134788-B2 Engineered prephenate dehydrogenases and arogenate dehydrogenases and methods of using the same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-11-05 US claimed
CN-118203664-A Composition containing at least one natural or synthetic N-alkylamide as active substance and method for producing same 埃利奥诺公司 2024-06-18 CN claimed
US-20230354864-A1 EXTRACT, CONSUMABLE PRODUCT AND METHOD FOR ENRICHING BIOACTIVE METABOLITE IN AN EXTRACT BRIGHTSEED, INC. 2023-11-09 US claimed
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION REVVITY HEALTH SCIENCES, INC. 2023-05-25 US claimed
US-11647776-B2 Extract, consumable product and method for enriching bioactive metabolite in an extract BRIGHTSEED, INC. (US) 2023-05-16 US claimed
CN-116064608-A Barley agmatine-bean acyl transferase gene HvACT2 and application thereof in improving disease resistance of barley 浙江大学中原研究院 2023-05-05 CN claimed
US-11549017-B2 NIR to SWIR fluorescent compounds for imaging and detection PERKINELMER HEALTH SCIENCES, INC. (US) 2023-01-10 US claimed
US-20190100654-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION REVVITY HEALTH SCIENCES, INC. 2019-04-04 US claimed
WO-2019067180-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION PERKINELMER HEALTH SCIENCES, INC. (US) 2019-04-04 WO claimed
WO-2019012525-A2 COMPOSITIONS COMPRISING HYDROXYCINNAMIC ACID AND RELATED CONJUGATES, ANALOGUES AND DERIVATIVES, AND METHODS OF USE THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2019-01-17 WO claimed
US-20180265880-A1 Arogenate dehydrogenase polynucleotides, polypeptides and methods of using the same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2018-09-20 US claimed
EP-2812345-B1 METHOD OF SYNTHESIZING PEPTIDES, PROTEINS AND BIOCONJUGATES UNIV NANYANG TECH (SG) 2017-11-22 EP claimed
US-9453044-B2 Method of synthesizing peptides, proteins and bioconjugates NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-09-27 US claimed
US-20150344519-A1 METHOD OF SYNTHESIZING PEPTIDES, PROTEINS AND BIOCONJUGATES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2015-12-03 US claimed
EP-2812345-A1 METHOD OF SYNTHESIZING PEPTIDES, PROTEINS AND BIOCONJUGATES Nanyang Technological University (SG) 2014-12-17 EP claimed
WO-2013119184-A1 METHOD OF SYNTHESIZING PEPTIDES, PROTEINS AND BIOCONJUGATES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2013-08-15 WO claimed
WO-2001053501-A2 GLUTATHIONE-S-TRANSFERASE NUCLEIC ACIDS AND POLYPEPTIDES AND METHODS OF USE THEREOF FACCHINI PETER JAMES (CA) 2001-07-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132413-A1 AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME PNP, RNGTT, DPYD NFKB1 1379/4885JUN 2497/4885NFE2L2 830/4885
US-20230354864-A1 EXTRACT, CONSUMABLE PRODUCT AND METHOD FOR ENRICHING BIOACTIVE METABOLITE IN AN EXTRACT HCAR2, HNMT, TYR NFKB1 2107/4885JUN 3988/4885NFE2L2 3727/4885
US-11549017-B2 NIR to SWIR fluorescent compounds for imaging and detection SMARCD1, SMARCE1, SMARCB1 NFKB1 2850/4885JUN 1629/4885NFE2L2 4283/4885
US-20190100654-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION SMARCD1, SMARCE1, SMARCB1 NFKB1 2850/4885JUN 1629/4885NFE2L2 4283/4885
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION SMARCD1, SMARCE1, SMARCB1 NFKB1 2850/4885JUN 1629/4885NFE2L2 4283/4885
US-20150344519-A1 METHOD OF SYNTHESIZING PEPTIDES, PROTEINS AND BIOCONJUGATES DNPEP, PTMS, QPCT NFKB1 1570/4885JUN 3915/4885NFE2L2 3847/4885
US-11647776-B2 Extract, consumable product and method for enriching bioactive metabolite in an extract HCAR2, HNMT, TYR NFKB1 2107/4885JUN 3988/4885NFE2L2 3727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.