SCHEMBL19829683

SCHEMBL19829683

CCOCCC1CCC(c2ccc(-c3ccc(C(F)(F)Oc4cc(F)c(F)c(F)c4)cc3)cc2)CC1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.34
SOAT1 P35610 1/20 0.34
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 2/20 0.31
CYP3A4 P08684 1/20 0.31
CCR2 P41597 3/20 0.30
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19829696 0.91 DGAT1 (0.32) DGAT1SOAT1ALDH1A1LMNAMAPT
SCHEMBL19829699 0.90 CYP2C9 (0.30) CYP2C9
SCHEMBL9911318 0.89 ALDH1A1 (0.42) DGAT1SOAT1ALDH1A1LMNAMAPT
SCHEMBL16789616 0.88 DGAT1 (0.36) DGAT1SOAT1ALDH1A1LMNAMAPT
SCHEMBL16789614 0.87 ALDH1A1 (0.36) DGAT1SOAT1ALDH1A1LMNAMAPT
SCHEMBL19829738 0.87 ALDH1A1 (0.32) DGAT1SOAT1ALDH1A1LMNAMAPT
SCHEMBL16789615 0.86 MAPT (0.35) DGAT1SOAT1ALDH1A1LMNAMAPT
SCHEMBL7729296 0.86 ALDH1A1 (0.44) ALDH1A1LMNAMAPTCYP2C9CYP3A4
SCHEMBL7729301 0.86 ALDH1A1 (0.44) ALDH1A1LMNAMAPTCYP2C9CYP3A4
SCHEMBL19829720 0.85 CYP3A4 (0.31) CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030347-A1 LIQUID CRYSTAL COMPOUND HAVING DIFLUOROMETHYLENEOXY GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed