SCHEMBL9911318

SCHEMBL9911318

CCCC1CCC(c2ccc(-c3ccc(C(F)(F)Oc4cc(F)c(F)c(F)c4)cc3)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 2/20 0.41
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
DGAT1 O75907 5/20 0.34
SOAT1 P35610 1/20 0.34
CYP3A4 P08684 1/20 0.33
CCR2 P41597 3/20 0.32
ESR2 Q92731 1/20 0.32
P2RY14 Q15391 2/20 0.32
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7729296 0.96 ALDH1A1 (0.44) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7729301 0.96 ALDH1A1 (0.44) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730315 0.95 ALDH1A1 (0.43) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730311 0.95 ALDH1A1 (0.43) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730309 0.95 ALDH1A1 (0.43) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL16789614 0.93 ALDH1A1 (0.36) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730684 0.93 ALDH1A1 (0.42) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730674 0.93 ALDH1A1 (0.42) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730676 0.93 ALDH1A1 (0.42) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL16789615 0.92 MAPT (0.35) ALDH1A1LMNAMAPTCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023799-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2018-07-17 US disclosed
US-20170342601-A1 CONJUGATE FIBERS WITH ENCAPSULATED LIQUID CRYSTAL AND CONJUGATE FIBER AGGREGATE JNC CORPORATION (JP) 2017-11-30 US disclosed
US-20170342601-A1 CONJUGATE FIBERS WITH ENCAPSULATED LIQUID CRYSTAL AND CONJUGATE FIBER AGGREGATE JNC CORPORATION (JP) 2017-11-30 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
EP-3235931-A1 COMPOSITE FIBER WITH ENCLOSED LIQUID CRYSTAL, AND COMPOSITE FIBER ARRANGEMENT JNC Corporation (JP) 2017-10-25 EP disclosed
US-20170240809-A1 COMPOUNDS HAVING A DIFLUOROCYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITIONS AND LIQUID CRYSTAL DISPLAY DEVICES JNC CORPORATION (JP) 2017-08-24 US disclosed
US-20170240809-A1 COMPOUNDS HAVING A DIFLUOROCYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITIONS AND LIQUID CRYSTAL DISPLAY DEVICES JNC CORPORATION (JP) 2017-08-24 US disclosed
US-9657229-B2 Liquid crystal compound having difluoromethyleneoxy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-05-23 US disclosed
US-9657229-B2 Liquid crystal compound having difluoromethyleneoxy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2017-05-23 US disclosed
EP-2960226-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2015-12-30 EP disclosed
EP-2957554-A1 LIQUID-CRYSTALLINE COMPOUND HAVING DIFLUOROMETHYLENEOXY GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2015-12-23 EP disclosed
US-20150159089-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2015-06-11 US disclosed
US-20150159089-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2015-06-11 US disclosed
US-8642142-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2014-02-04 US disclosed
US-8642142-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2014-02-04 US disclosed
US-8367167-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-02-05 US disclosed
US-8367167-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-02-05 US disclosed
US-20120298917-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2012-11-29 US disclosed
US-20120138852-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10023799-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device PIEZO1, ROCK1, RCC1 ALDH1A1 2496/4885LMNA 2467/4885MAPT 61/4885
US-20170240809-A1 COMPOUNDS HAVING A DIFLUOROCYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITIONS AND LIQUID CRYSTAL DISPLAY DEVICES OCIAD2, CCDC22, CALCOCO2 ALDH1A1 1952/4885LMNA 3469/4885MAPT 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.