SCHEMBL19829703

SCHEMBL19829703

CCOCC1CCC(c2ccc(-c3ccc(C(F)(F)Oc4ccc(C(F)(F)F)c(F)c4)cc3)cc2)CC1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 6/20 0.34
CYP11B2 P19099 6/20 0.34
DGAT1 O75907 3/20 0.33
SOAT1 P35610 1/20 0.33
KIF11 P52732 7/20 0.32
KDM1A O60341 1/20 0.32
CCR2 P41597 1/20 0.31
KCNH2 Q12809 1/20 0.31
CHRNA7 P36544 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19829696 0.88 DGAT1 (0.32) DGAT1SOAT1CCR2KCNH2
SCHEMBL7735095 0.87 KDM1A (0.36) CYP11B1CYP11B2DGAT1SOAT1KIF11
SCHEMBL7735093 0.87 KDM1A (0.36) CYP11B1CYP11B2DGAT1SOAT1KIF11
SCHEMBL7729967 0.86 ALDH1A1 (0.41) CYP11B1CYP11B2KDM1ACHRNA7
SCHEMBL7729964 0.86 ALDH1A1 (0.41) CYP11B1CYP11B2KDM1ACHRNA7
SCHEMBL7731204 0.84 ALDH1A1 (0.35) KIF11KDM1ACHRNA7
SCHEMBL7722999 0.84 KDM1A (0.34) CYP11B1CYP11B2DGAT1SOAT1KDM1A
SCHEMBL7722997 0.84 KDM1A (0.34) CYP11B1CYP11B2DGAT1SOAT1KDM1A
SCHEMBL7722994 0.84 KDM1A (0.34) CYP11B1CYP11B2DGAT1SOAT1KDM1A
SCHEMBL7731207 0.84 ALDH1A1 (0.35) KIF11KDM1ACHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030347-A1 LIQUID CRYSTAL COMPOUND HAVING DIFLUOROMETHYLENEOXY GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed