Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831094 | 0.88 | ALOX15 (0.66) | ALOX15HPGDKMT2AMEN1MAPK1 | |
| SCHEMBL19831222 | 0.87 | ALOX15 (0.56) | ALOX15HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL19831195 | 0.87 | ALOX15 (0.69) | ALOX15HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL2885143 | 0.84 | HPGD (0.61) | HPGDALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL8794611 | 0.81 | ALDH1A1 (0.66) | ALOX15HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL19831097 | 0.81 | ALOX15 (0.62) | ALOX15HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL19831031 | 0.78 | ALOX15 (0.77) | ALOX15HPGDALDH1A1 | |
| SCHEMBL19831216 | 0.78 | ALOX15 (0.65) | ALOX15 | |
| SCHEMBL8545161 | 0.76 | KDM4E (0.64) | ALOX15HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL9938004 | 0.76 | GAA (0.60) | ALOX15HPGDALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |