Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 16/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831042 | 0.91 | ALOX15 (0.72) | ALOX15HPGDALDH1A1CYP1A2XBP1 | |
| SCHEMBL19831094 | 0.88 | ALOX15 (0.66) | ALOX15HPGDMEN1TSHRMAPK1 | |
| SCHEMBL19831222 | 0.88 | ALOX15 (0.56) | ALOX15HPGDMEN1TSHRMAPK1 | |
| SCHEMBL19831036 | 0.83 | ALOX15 (0.74) | ALOX15HPGDALDH1A1CYP1A2XBP1 | |
| SCHEMBL19831031 | 0.81 | ALOX15 (0.77) | ALOX15HPGDALDH1A1CYP1A2XBP1 | |
| SCHEMBL19831067 | 0.81 | ALOX15 (0.53) | ALOX15HPGDALDH1A1MEN1TSHR | |
| SCHEMBL8793660 | 0.78 | ALOX15 (0.85) | ALOX15HPGDALDH1A1CYP1A2XBP1 | |
| SCHEMBL17373720 | 0.77 | ALDH1A1 (0.69) | ALOX15HPGDALDH1A1CYP1A2XBP1 | |
| SCHEMBL7205567 | 0.76 | ALDH1A1 (0.42) | ALOX15HPGDALDH1A1CYP1A2XBP1 | |
| SCHEMBL3222794 | 0.76 | RAB9A (0.64) | HPGDALDH1A1MEN1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |