Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.35 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969677 | 0.90 | NISCH (0.48) | NISCHMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1983146 | 0.72 | NISCH (0.45) | NISCHNPC1RAB9ATTBK1TTBK2 | |
| SCHEMBL4722556 | 0.69 | ALDH1A1 (0.31) | NISCHCYP2C9ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL943191 | 0.69 | ALDH1A1 (0.38) | CYP2C9ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL876246 | 0.69 | ALDH1A1 (0.43) | NISCHMEN1KMT2AADRA2AADRA2C | |
| SCHEMBL2221480 | 0.68 | F2 (0.58) | ADRA2AADRA1AKCNH2CYP2D6 | |
| SCHEMBL3708834 | 0.64 | KEAP1 (0.43) | NISCHMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16313542 | 0.64 | NPC1 (0.53) | NISCHNPC1RAB9ACYP2C9ALDH1A1 | |
| SCHEMBL10753747 | 0.61 | NISCH (0.40) | NISCHMEN1KMT2ANPC1RAB9A | |
| SCHEMBL83814 | 0.61 | TEAD4 (0.74) | MEN1KMT2AGAACYP2C9TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6761909-B1 | COMPRESSED ANTISOLVENT FLUID PRECIPITATES PARTICLES; ORGANIC COSOLVENT SYSTEM; BIOCOMPATIBLE POLYMER FOR PULMONARY SUSTAINED INSULIN RELEASE; INHALANT POWDER; SOLVENT EXTRACTION | RXKINETIX, INC. | 2004-07-13 | — | — | US | disclosed |