SCHEMBL19831576

SCHEMBL19831576

CN1C(=O)c2c(ncn2C)N(C)C1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24611645 0.80
SCHEMBL20182573 0.78
SCHEMBL20151714 0.77
SCHEMBL19472255 0.77 SMN1; SMN2 (0.34)
SCHEMBL19472287 0.77 AMPD2 (0.38)
SCHEMBL24611657 0.76
SCHEMBL20205691 0.76 ALDH1A1 (0.32)
SCHEMBL19607708 0.75
SCHEMBL20205955 0.75 L3MBTL1 (0.43)
SCHEMBL22085071 0.75 SMN1; SMN2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572565-B2 Inducible control of gene expression TRUSTEES OF BOSTON UNIVERSITY (US) 2023-02-07 US disclosed
US-20220025381-A1 INDUCIBLE CONTROL OF GENE EXPRESSION TRUSTEES OF BOSTON UNIVERSITY (US) 2022-01-27 US disclosed
WO-2020157668-A1 THEOPHYLLINE DERIVATIVES WITH NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE USE ISAGRO S.P.A. (IT) 2020-08-06 WO disclosed
US-20200222537-A1 BIOPHOTONIC COMPOSITIONS AND USES THEREOF KLOX TECHNOLOGIES LIMITED (IE) 2020-07-16 US disclosed
US-10696972-B2 Method for improving learning ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2020-06-30 US disclosed
US-20180030453-A1 METHOD FOR IMPROVING LEARNING ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2018-02-01 US disclosed