Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831609 | 0.86 | HDAC1 (1.00) | HDAC1HDAC2MEN1KMT2ARXFP1 | |
| SCHEMBL19831610 | 0.85 | HDAC1 (0.81) | HDAC1HDAC2MEN1KMT2ARXFP1 | |
| SCHEMBL15553332 | 0.82 | HDAC1 (1.00) | HDAC1HDAC2MEN1KMT2AHDAC3 | |
| SCHEMBL29903248 | 0.82 | HDAC1 (1.00) | HDAC1HDAC2MEN1KMT2AHDAC3 | |
| SCHEMBL17833424 | 0.80 | MEN1 (1.00) | HDAC1HDAC2MEN1KMT2ARXFP1 | |
| SCHEMBL3752732 | 0.80 | HDAC1 (0.78) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL4971049 | 0.80 | HDAC1 (0.54) | HDAC1HDAC2MEN1KMT2ANPC1 | |
| SCHEMBL5089315 | 0.80 | HDAC1 (0.59) | HDAC1HDAC2MEN1KMT2ARXFP1 | |
| SCHEMBL15551664 | 0.79 | HDAC1 (1.00) | HDAC1HDAC2MEN1KMT2ANPC1 | |
| SCHEMBL8241099 | 0.79 | HDAC1 (0.76) | HDAC1HDAC2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018019084-A1 | BENZAMIDE COMPOUND AND USE THEREOF IN PREPARING DRUGS INHIBITING CANCER CELL PROLIFERATION AND/OR TREATING CANCER | 北京化工大学 | 2018-02-01 | — | — | WO | disclosed |