Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 7/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.78 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | CASP3 | P42574 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831610 | 0.90 | HDAC1 (0.81) | HDAC1HDAC2HDAC3SENP7NPC1 | |
| SCHEMBL19831611 | 0.88 | HDAC1 (0.78) | HDAC1HDAC2HDAC3SENP7NPC1 | |
| SCHEMBL19831685 | 0.88 | HDAC1 (0.78) | HDAC1HDAC2HDAC3SENP7NPC1 | |
| SCHEMBL19831684 | 0.88 | HDAC1 (0.78) | HDAC1HDAC2HDAC3SENP7NPC1 | |
| SCHEMBL19831686 | 0.86 | SENP7 (0.79) | HDAC1HDAC2HDAC3SENP7NPC1 | |
| SCHEMBL19831608 | 0.86 | HDAC1 (0.75) | HDAC1HDAC2HDAC3SENP7NPC1 | |
| SCHEMBL28188848 | 0.84 | MEN1 (0.77) | HDAC1HDAC2HDAC3SMN1; SMN2MEN1 | |
| SCHEMBL1066808 | 0.82 | HDAC1 (0.69) | HDAC1HDAC2HDAC3SENP7NPC1 | |
| SCHEMBL28593279 | 0.80 | MAPT (0.73) | HDAC1HDAC2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17833424 | 0.80 | MEN1 (1.00) | HDAC1HDAC2SENP7NPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018019084-A1 | BENZAMIDE COMPOUND AND USE THEREOF IN PREPARING DRUGS INHIBITING CANCER CELL PROLIFERATION AND/OR TREATING CANCER | 北京化工大学 | 2018-02-01 | — | — | WO | disclosed |