Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642038 | 0.92 | RBP4 (0.32) | RBP4 | |
| SCHEMBL23642039 | 0.83 | RBP4 (0.32) | RBP4 | |
| SCHEMBL19297287 | 0.80 | RBP4 (0.38) | RBP4 | |
| SCHEMBL17229732 | 0.72 | CREBBP (0.45) | — | |
| SCHEMBL19413422 | 0.71 | DPP4 (0.41) | RBP4 | |
| SCHEMBL22473874 | 0.70 | CREBBP (0.38) | RBP4 | |
| SCHEMBL17229804 | 0.70 | RBP4 (0.35) | RBP4 | |
| SCHEMBL17229771 | 0.68 | RBP4 (0.40) | RBP4 | |
| SCHEMBL20462838 | 0.68 | RBP4 (0.36) | RBP4 | |
| SCHEMBL17229701 | 0.67 | CREBBP (0.47) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421720-B2 | Octahydrocyclopentapyrroles, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-09-24 | — | — | US | disclosed |
| US-20180030060-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030060-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | HRH4, HRH3, HRH2 | RBP4 1884/4885 |
| US-10421720-B2 | Octahydrocyclopentapyrroles, their preparation and use | CLN6, ALDH1A2, C1S | RBP4 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.