SCHEMBL19831883

SCHEMBL19831883

C(=C(/Cc1ccccc1)c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5ccccc5c4)cc3)cc2)cc1)\c1ccc(-c2ccccc2)c2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 3/20 0.38
ALOX5 P09917 3/20 0.38
EGFR P00533 1/20 0.35
SGK1 O00141 1/20 0.34
PDE7A Q13946 1/20 0.33
PDE7B Q9NP56 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
KAT6A Q92794 1/20 0.32
ACHE P22303 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2B Q13224 1/20 0.32
HSD17B1 P14061 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19784597 0.84 ESR1 (0.36) PTGESALOX5PDE7APDE7BMEN1
SCHEMBL19784912 0.80 ALDH1A1 (0.38) EGFRMEN1MAPK1KMT2ASMN1; SMN2
SCHEMBL25891975 0.79 ESR1 (0.46) PTGESALOX5MEN1MAPTKMT2A
SCHEMBL24901303 0.77 ESR1 (0.43) PTGESALOX5MEN1MAPTKMT2A
SCHEMBL20313386 0.76 GSTP1 (0.46) PTGESALOX5MEN1MAPTMAPK1
SCHEMBL20345317 0.75 ACP3 (0.36) PTGESALOX5SMN1; SMN2RXRARXRB
SCHEMBL20313404 0.75 GSTP1 (0.44) PTGESALOX5MEN1MAPTMAPK1
SCHEMBL24901218 0.74 HSD17B1 (0.41) ALOX5MEN1MAPTMAPK1KMT2A
SCHEMBL24307821 0.73 ESR1 (0.40) ALOX5MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL22136224 0.73 PTGS1 (0.40) GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018021737-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2018-02-01 WO disclosed