Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831977 | 0.81 | TAAR1 (0.39) | SLC6A2SLC6A3SLC6A4TAAR1MAOA | |
| SCHEMBL13692457 | 0.80 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL11276473 | 0.80 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL2222710 | 0.73 | TAAR1 (0.56) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL13692532 | 0.72 | PNMT (0.57) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL3885817 | 0.72 | PNMT (0.57) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL268275 | 0.71 | SLC6A2 (0.66) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL8029239 | 0.71 | SLC6A2 (0.66) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL13692527 | 0.71 | SLC6A2 (0.66) | SLC6A2SLC6A3SLC6A4PNMTTAAR1 | |
| SCHEMBL23640995 | 0.71 | TAAR1 (0.39) | SLC6A2SLC6A3SLC6A4TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018023072-A2 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUNOVION PHARMACEUTICALS, INC. (US) | 2018-02-01 | — | — | WO | disclosed |