Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | PNMT | P11086 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692457 | 1.00 | SLC6A2 (0.54) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL2222710 | 0.86 | TAAR1 (0.56) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL5018858 | 0.81 | TAAR1 (0.44) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL19831978 | 0.80 | SLC6A2 (0.47) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL2426412 | 0.77 | AKR1B1 (0.43) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL15083012 | 0.77 | AKR1B1 (0.43) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL18537078 | 0.77 | TAAR1 (0.41) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL8790684 | 0.77 | TAAR1 (0.46) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL3885817 | 0.77 | PNMT (0.57) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 | |
| SCHEMBL13692532 | 0.77 | PNMT (0.57) | SLC6A2SLC6A3PNMTTAAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174603-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2024-05-30 | — | — | US | disclosed |
| EP-0064487-A1 | New substituted 3-(parasubstituted)phenoxy-1-alkylamino-propanol-2-s, as well as process for their preparation, pharmaceutical preparations containing same, and method for treating cardiac failure | Aktiebolaget Hässle (SE) | 1982-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174603-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | PPM1A, PPP2CA, PPP3CA | SLC6A2 3829/4885SLC6A3 4551/4885PNMT 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.