Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CHAT | P28329 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19832928 | 0.76 | DHODH (0.32) | NOS3NOS1NOS2PYGLDHODH | |
| SCHEMBL19832828 | 0.73 | PNMT (0.30) | — | |
| SCHEMBL19824074 | 0.72 | AKR1C3 (0.38) | NOS3NOS1NOS2CHATPTGS2 | |
| SCHEMBL9967775 | 0.71 | CHAT (0.50) | NOS3NOS1NOS2PYGLALDH1A1 | |
| SCHEMBL10053127 | 0.71 | TYR (0.39) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A4 | |
| SCHEMBL19824200 | 0.69 | — | — | |
| SCHEMBL21077672 | 0.69 | SLC6A4 (0.40) | PYGLSLC6A4CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL14329254 | 0.69 | GRIK1 (0.33) | PYGLALDH1A1CHATGRIK1GRIK2 | |
| SCHEMBL4027034 | 0.69 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A4 | |
| SCHEMBL24987704 | 0.69 | TRPV4 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934142-B1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-01-31 | — | — | EP | disclosed |