Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 12/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987767 | 0.92 | VCAM1 (0.46) | VCAM1MEN1KMT2ALMNAPOLB | |
| SCHEMBL1981967 | 0.89 | VCAM1 (0.41) | VCAM1MEN1KMT2ALMNAPOLB | |
| SCHEMBL1985446 | 0.80 | MEN1 (0.48) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL1984793 | 0.77 | BCL2 (0.41) | LMNAPOLBMAPTMAPK1NPSR1 | |
| SCHEMBL11506969 | 0.74 | VCAM1 (0.46) | VCAM1MEN1KMT2ALMNAPOLB | |
| SCHEMBL1988552 | 0.72 | TSHR (0.49) | POLBMAPTALDH1A1 | |
| SCHEMBL11625311 | 0.72 | ALDH1A1 (0.48) | VCAM1MEN1KMT2ALMNAMAPT | |
| SCHEMBL30955236 | 0.70 | VCAM1 (0.56) | VCAM1MAPK1 | |
| SCHEMBL2873685 | 0.70 | VCAM1 (0.56) | VCAM1MAPK1 | |
| SCHEMBL12591651 | 0.70 | VCAM1 (0.53) | VCAM1MEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2337781-A2 | ANTI-VIRAL COMPOUNDS TO TREAT HCV INFECTION | Abbott Laboratories (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010144646-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2010-12-16 | — | — | WO | disclosed |