Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1988552 | 0.92 | TSHR (0.49) | POLBTSHRALDH1A1MAPTGSK3B | |
| SCHEMBL1984793 | 0.84 | BCL2 (0.41) | POLBMAPTHTT | |
| SCHEMBL1983283 | 0.80 | VCAM1 (0.41) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL1981967 | 0.79 | VCAM1 (0.41) | MEN1KMT2APOLBTSHRALDH1A1 | |
| SCHEMBL1981965 | 0.75 | PTPRC (0.51) | MEN1KMT2APOLBTSHRALDH1A1 | |
| SCHEMBL85535 | 0.73 | MEN1 (0.64) | MEN1KMT2APOLBALDH1A1CRHBP | |
| Fluoride SCHEMBL27503363 | 0.71 | MEN1 (0.62) | MEN1KMT2APOLBALDH1A1CRHBP | |
| SCHEMBL19025562 | 0.71 | MEN1 (0.62) | MEN1KMT2APOLBALDH1A1CRHBP | |
| SCHEMBL11869078 | 0.71 | MEN1 (0.54) | MEN1KMT2APOLBALDH1A1CRHBP | |
| SCHEMBL335896 | 0.70 | TSHR (0.49) | POLBTSHRALDH1A1MAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2337781-A2 | ANTI-VIRAL COMPOUNDS TO TREAT HCV INFECTION | Abbott Laboratories (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010144646-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2010-12-16 | — | — | WO | disclosed |